After serving a two-match ban for a red card during the qualifiers, Isaac Vorsah will start for the Black Stars against Guinea on Wednesday night.
It will be his first start at the 2012 African Cup of Nations, where he pairs up in central defence with John Boye. The Hoffenheim player is one of the two changes made Goran Stevanovic to the side that beat Mali 2-0.
Samuel Inkoom plays in right midfield ahead of Sulley Muntari.
Official XI: Adam Kwarasey, John Paintsil, Masahudu Alhassan, Isaac Vorsah, John Boye, Anthony Annan, Samuel Inkoom, Agyemang Badu, Asamoah Gyan, Kwadwo Asamoah, Andre Ayew
Subs: Daniel Adjei, Daniel Opare, Lee Addy, Jonathan Mensah, Sulley Muntari, Mohammed Abu, Jordan Ayew, Charles Takyi, Prince Tagoe, Derek Boateng, Ernest Sowah, John Mensah